Levitra Generic Online
Levitra contains active ingredient vardenafil. Levitra is issued the German firm Bayer. Active ingredient is its part vardenafil which belongs to the class of inhibitors of phosphodiesterase-5 (FDE-5). All drugs from this pharmaceutical group are means for elimination of erectile dysfunction.
The real Levitra is issued in two forms: usual tablets in a protective cover and tablets soluble in an oral cavity (Levitra ODT). The last are much more expensive, but lead to faster development of positive effect.Relaxation of muscles of cavernous bodies of a penis and dilatation of the vessels which are contained in it is the cornerstone of development of an erection. Leads these processes to filling of cavernous bodies with blood that is shown in the form of an erection.During sexual excitement of a cell of an internal cover of arteries of a penis begin to develop NO.
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Nitrogen oxide pulls for itself formation of guanylate cyclase and increase in formation of cGMF in smooth muscles of cavernous bodies. Enzyme phosphodiesterase-5 splits cGMF, controlling degree and duration of an erection.
Vardenafil who is Levitra’s part blocks activity of FDE-5 enzyme. It leads to accumulation of cGMF, strengthening of relaxation of smooth muscles of a penis, inflow of blood and development of an erection.
Levitra interacts mainly with FDE-5. It is 15 – 1000 times more active concerning this form of enzyme, than concerning other phosphodiesterases.
Levitra is shown when there are problems with an erection. Drug allows to cope as with various age and organic problems, and with psychogenic erectile dysfunction.
Levitra cannot be applied in the following situations:
- Intolerance of drug and active ingredient, including allergy;
- Reception of nitrozovazodilatators (nitroglycerine, Isoketum, Nitrosprey and etc);
- Intake of inhibitors of CYP3A4 enzyme (antifungiosus ketokonazol and itraconazol, antibiotics erythromycin and claritromucin, antiviral ritonavir and indanavir);
- Existence of diseases of a cardiovascular system (angina, heart failure).
Treat relative contraindications:
- Any deformations of a penis;
- Tendency to a priapism (a non-control erection without sexual excitement) any origin;
- The increased risk of development of bleedings;
- Aggravation of a peptic ulcer of a stomach, duodenum.
Concerning some states there is no information concerning Levitra’s use. In this regard, does not recommend to apply it in order to avoid unforeseen reactions at:
- Liver failure;
- Heavy renal failure;
- Arterial blood pressure less than 90/60 mm Hg;
- The myocardial infarction or a stroke transferred to the last half a year;
- For the first time the arisen or progressing angina;
- Diseases of a retina of any origin.
Among undesirable effects at Levitra the same generally prevail, as at Viagra, but they meet 1.5 – 2 times more rare:
- Head pains;
- Feeling of dizziness;
- Face reddening;
- Congestion of a nose;
- Digestive disturbance.